Kevin Spelman - molecular bio of immunomodulators

From the AHG symposium

Kevin Spelman
Immunomodulators: botanical medicines that through the dynamical regulation of informational molecules alter the activity of the immune systems.

Cytokines and the cytokine theory of disease (Czura, CJ 2005): overproduction of cytokines can cause the clinical manifestations of disease. But it can begin on an emotional level (anger/shame as opposed to medidative states) - then as cytokines levels increase, disease manifests: first depression, pain, anorexia. Then, psoriasis, colitis. Then, tissue damage and arthritis. Finally, shock and organ failure.

Tumor necrosis factor (TNF) and other cytokines like Epidermal Growth Factor stimulate a series of intracellular changes that ultimately have effects in the nucleus - on genetic expression. When, in researching botanicals, we look at                                           the  nucleus, we're getting somewhere.

Lisa Ganora - synergy in botanical medicines

From the AHG Symposium
Lisa Ganora - synergy in botanical medicines
The scientific research process makes it difficult to research more than a small handful of chemicals at a time. Considering that, by some estimates, botanicals contain up to 10,000 active constituents, scientific research runs up against a limit very quickly. Fortunately, we have a practical use history to turn to: we've been eating these plants for a long time with no harm.

Polymolecular approaches, which rely on synergy, have a unique ability to interface with the complex biological system of the human being. Plants provide this. Huge difference compared to pharmaceutical agents. Additionally, pharmaceuticals are very new on the scene. And most aren't cheap (whereas plants...)

The need for long-term thinking in medicine: Cinnamon as a case study


Here in Vermont, we are approaching the first anniversary of a storm that, over less than a day, poured an incredible amount of rain over the mountains, down the streams, and into narrow river valleys. The hill towns were quickly overwhelmed and literally swept away on huge torrents of water. These types of events are outliers, “hundred-year” floods. We tend not to think about them until they happen. If a river floods one spring, and washes away our garden, we could just build a retaining wall and be fine for years. But in Vermont, it seems that sort of thought process may have contributed to the severity of last summer’s event: narrower valleys, more constrained riverbeds, actually increased the torrent’s force and destructive power. As we rebuild, civil engineers are taking this into account.

Urban Moonshine herbal conference report


The recent week of warmth and humidity has taken a turn towards cooler weather today, and the south winds are freshening up and blowing in across the lake from the northwest now. But the full height of Summer’s glory was on display this Saturday, when over one hundred people from across Vermont and beyond attended Urban Moonshine’s first annual herb conference and the evening festivities that followed. I had an amazing time.

Aromatic plants – cultivating the scented garden within

It is legend that, some twenty-five hundred years ago, a ruler of  Babylon (or was it Niniveh?) commissioned a wondrous garden, terraced up from the flat plains between the rivers of the Fertile Crescent. Its levels were built of huge slabs of stone, elaborately carved and supported by high vaulted colonnades. Huge amounts of soil were transported to create hills and fields in this garden many, many feet above street level. Sundry species of trees, shrubs, flowers and herbs were brought in to plant its winding paths. Using giant corkscrew pumps, thousands of gallons of water were moved against gravity on a daily basis to keep the garden lush and green. The ancient historians named it one of the seven wonders of the world, and marveled at this oasis, high above the incessant bustle of the city, smoothed with endless marble and steeped in a deep, seductive fragrance from the constant bloom of aromatic plants.

The Natural Products Industry that Isn’t


                A few evenings ago I was sitting on a rough cedar deck, watching sunlight orange across the tops of the poplar and maple canopy, and thinking how nice it was to be visiting my friend’s house in the forest: the nestled feeling, the total privacy, the familiar smells. He confessed  that, sometimes, he too liked to imagine his house from the perspective of a guest, walking through his gardens, up the wooden steps, and into the kitchen with the eye of an outsider, taking the time to appreciate it without the preconceptions and perceptual habits that develop after living in a place for an extended period of time. Perhaps it was the effects of the mixture of Schisandra kombucha, gin, and tonic water we were drinking, but this short exercise in mindfulness seemed to me as both a useful habit to practice and also a profoundly important skill for the modern human. We are so entrenched in our politics, our communities, our niches and worldviews that, without occasionally looking at life from outside the fences, we might run the risk of missing out on an important and useful perspective.

A brief and practical introduction to pulse and tongue assessment


Any assessment or diagnostic technique that seeks to make sense of what’s happening inside the human system is inherently pretty complex – be it a modern tool such as a CT scanner, or a traditional device such as the stethoscope. Interpretation is tricky, and the background knowledge required can often be intimidating. While using the tongue and pulse to get a glimpse inside the human body is not an exception, one can nevertheless glean really useful, actionable information with even a basic understanding of the technique. This basic understanding can become richer and deeper with ongoing practice. The complexity evidenced in traditional texts on the subject should not be a reason to keep you from experimenting!

Plant allies for winter health


Enhancing immune activity

Why: Herbal allies to combat respiratory infection as it begins.

Echinacea, Andrographis, Elderberry, Hyssop, Garlic, Osha

These agents provide an immediate “boost” to immune function, particularly the body’s ability to produce antibodies against viral infections. Will shorten the duration of common winter infections, and can also be used longer-term as preventative agents particularly for those more at risk.

Plant medicine heals more than just people


We often discuss how effective plants can be at supporting and gently bringing human beings back to a state of "wellness" (meaning that resiliency, vibrancy, passion are maximized). I've spent a lot of time exploring how this happens, reading through the historical record and perusing modern research, and on balance it seems pretty clear that medicinal herbs, trees, mushrooms and more are good at helping folks in need. But that's not what I want to discuss today.









Joyful herbs for the darker days


All of us feel the loss of daylight to a certain extent. For some, it may be occasional sluggishness, less motivation to get outside and exercise, or less of a desire to spend time with friends and family. Others may feel even deeper withdrawal, or experience less control over anxiety and the sometimes overwhelming responsibilities of daily life. To a certain extent, the culture has tried to address this by consistently packing in times of remembrance, celebration, and family during the darkest months of the year – but by the time it’s all over (or even during the often stressful holidays), there are still many months of darker days left and it is usually at this time that folks express the desire for more fun, more joy, more light.